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Texas - Wikipedia
Texas (/ ˈtɛksəs / ⓘ TEK-səss) [c] is a state in the United States. It borders the American states of Louisiana to the east, Arkansas to the northeast, Oklahoma to the north, and New Mexico to the west. To the south and southwest, it has an international border with the Mexican states of Chihuahua, Coahuila, Nuevo León, and Tamaulipas, along a natural boundary formed by the Rio Grande ...

Texas.gov | The Official Website of the State of Texas
Texas.gov is the official website of the State of Texas. From here, we’ll guide you to online services, resources, and information around our great state.

Texas State Map | USA | Detailed Maps of Texas (TX)
Description: This map shows boundaries of countries, states boundaries, the state capital, counties, county seats, cities, towns, Gulf of Mexico, islands and national parks in Texas.

Texas | Map, Flag, Population, History, Geography, & Facts | Britannica
Texas is a constituent state of the U.S. It became the 28th state of the union in 1845. It is bordered on the north by Oklahoma, on the northeast by Arkansas, on the east by Louisiana, on the south by Mexico, and on the west by New Mexico. Its capital city is Austin, in the south-central part of the state.

History of Texas - Wikipedia
Texas lies at the juncture of several major cultural areas of Pre-Columbian North America: the Southwestern, Southern Plains, Southeastern Woodlands, and Aridoamerica. Several major precontact groups with ties to Texas, known from Indigenous oral history, linguistics, and archaeology, include: [7] Ancestral Pueblo peoples from the upper Rio Grande region, centered west of Texas Mound Builders ...

Texas Maps & Facts - World Atlas
Physical map of Texas showing major cities, terrain, national parks, rivers, and surrounding countries with international borders and outline maps. Key facts about Texas.

Vacations in Texas | Trip Planning & Inspiration
Build smarter itineraries to travel Texas with tools, routes, and seasonal highlights across cities and regions.

Texas - Simple English Wikipedia, the free encyclopedia
Texas (/ ˈtɛksəs /, also locally / ˈtɛksɪz / American Spanish: [tejaz] [8]), officially the State of Texas, is a state in the South Central Region of the United States. It is the second largest US state by total area (after Alaska) with 268,596 sq mi (695,662 km 2) and population (after California) with over 29 million people as of 2020. Its largest cities are Houston, Dallas, Fort Worth ...

About Texas.gov
About Texas.gov Texas.gov is the official website of the State of Texas. It’s a trusted and friendly place for Texans to access government services and information.

Texas - State, Population & Map | HISTORY
Texas experienced tremendous growth in the late 19th and early 20th centuries, driven by the cattle and cotton industries, railroads, and the 1901 discovery of oil at Spindletop.

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A Mother's Hidden OCD Battle And Road To Recovery  KHOU
One genetic map could rewrite how we understand mental health  Texas A&M Stories
Video Family Secrets Full Episode: Battling OCD  ABC News - Breaking News, Latest News and Videos
Southeast Texas mental health leaders push action at annual luncheon  Beaumont Enterprise
Med Harmony Offering TMS Therapy in Fort Worth, Texas  The National Law Review
US 2026 Instructor Crossover Dates Announced By PSS  DeeperBlue.com
/Researchers discover a new neural biomarker for OCD  Texas Children's
OCD expert Elizabeth McIngvale, Ph.D., shares personal OCD journey, treatment options for patients  TMC Houston
1 Million Steps for OCD Walk makes its way to Dallas in September  Lakewood/East Dallas Advocate
US boxer Virginia Fuchs on OCD, Tokyo Olympics, Claressa Shields  olympics.com
Merry Christmas, from Ray Overbey  pacaf.af.mil
The challenge of treating OCD patients | Registered Dental Hygienists  rdhmag.com
Shadow of a Doubt, by Andrew Kay  Harper's Magazine
Elisa R. Canales Obituary Apr 16, 2026  Rushing-Estes-Knowles Mortuary
Sister MARY IMMACULATE of the HOLY SPIRIT, O.C.D. (Stella Elizabeth Warner) Obituary Nov 9, 2023  Harper & Lucas Funeral Home & Cremation Services

Common Cardiovascular Symptoms & Warning Signs

Chest Pain or Pressure (Angina) — Sensation of squeezing, fullness, or tightness in the center of the chest that may radiate to the jaw, neck, back, or arm.
Shortness of Breath (Dyspnea) — Difficulty breathing or feeling winded during routine activities, exertion, or while lying flat in bed.
Palpitations or Irregular Heartbeat — Sensations of a racing, fluttering, pounding, or skipping heart rate.
Unexplained Dizziness or Lightheadedness — Sudden feelings of faintness, loss of balance, or near-syncope linked to decreased blood flow to the brain.
Swelling in the Extremities (Edema) — Fluid retention causing notable swelling in the legs, ankles, feet, or abdomen.
Unusual Fatigue and Weakness — Persistent tiredness or exhaustion during simple daily tasks, often an early warning sign of heart failure.
Cold Sweats or Diaphoresis — Sudden onset of unexplained profuse sweating accompanied by chest discomfort or anxiety.
Cyanosis or Pale Skin Tone — A bluish or abnormally pale discoloration of the skin, lips, or nail beds due to poor oxygen circulation.
Persistent Coughing or Wheezing — Chronic cough producing white or pink blood-tinged mucus caused by fluid accumulation in the lungs.
Pain in the Extremities (Claudication) — Cramping or aching in the calves, thighs, or hips during walking, indicating peripheral artery disease.

Current Cardiovascular Treatments

Dual GIP/GLP-1 Receptor Agonists — Advanced metabolic agents like tirzepatide cut major adverse cardiovascular events, reduce systemic vascular inflammation, and improve heart failure outcomes.
Pulsed-Field Ablation (PFA) — Non-thermal electroporation therapy replacing traditional radiofrequency ablation to treat atrial fibrillation with greater tissue selectivity and safety.
SGLT2 Inhibitor Therapy — Guideline-directed medical treatment (e.g., dapagliflozin, empagliflozin) initiated early to reduce hospitalizations and mortality across heart failure spectrums.
Targeted siRNA & Lipid Gene Therapy — Small interfering RNA injectables (like inclisiran) and gene-editing therapies (VERVE-102) providing long-term LDL-C reduction with single-dose schedules.
Transcatheter Valve Therapies (TAVR / TMVR) — Minimally invasive catheter interventions for replacing or repairing severe aortic, mitral, and tricuspid valve stenosis/regurgitation without open-heart surgery.
Aldosterone Synthase Inhibitors — Targeted hormonal pathway medications, such as baxdrostat, designed to treat treatment-resistant hypertension by lowering aldosterone production.
Left Bundle Branch Area Pacing (LBBAP) — Conduction system pacing delivering direct physiological resynchronization as a superior alternative to traditional cardiac resynchronization therapy.
Dual Endothelin Receptor Antagonists — Novel oral therapies like aprocitentan used in combination regimes to target resistant high blood pressure through specialized vascular pathways.
Targeted Anti-Inflammatory Agents — Low-dose colchicine and specialized anti-inflammatory protocols aimed directly at preventing plaque rupture and reducing residual cardiovascular risk.
Mechanical Decompression Systems — Endovascular venous balloon technology and advanced left ventricular assist devices designed to acutely unload intracardiac pressures during heart failure crises.

Key Milestones in Cardiovascular History

Discovery of Blood Circulation (1628) — William Harvey published De Motu Cordis, demonstrating for the first time that blood circulates continuously through the body pumped by the heart.
Invention of the Stethoscope (1816) — René Laennec invented the wooden stethoscope, allowing physicians to auscultate and diagnose internal cardiac sounds non-invasively.
First Human Electrocardiogram (1902) — Willem Einthoven developed the string galvanometer to record the electrical activity of the heart, inventing the modern ECG.
First Human Cardiac Catheterization (1929) — Werner Forssmann performed the first successful cardiac catheterization on himself, opening the path for modern interventional cardiology.
Launch of the Framingham Heart Study (1948) — A landmark long-term epidemiological study began, establishing major risk factors like high blood pressure, cholesterol, and smoking.
Development of the Cardiopulmonary Bypass (1953) — John Gibbon successfully used a heart-lung machine on a human patient, enabling modern open-heart surgery.
First Successful Human Heart Transplant (1967) — Dr. Christiaan Barnard performed the world's first human-to-human heart transplant in Cape Town, South Africa.
First Coronary Angioplasty (1977) — Andreas Grüntzig performed the first successful percutaneous transluminal coronary angioplasty (PTCA) to open blocked arteries.
Introduction of Coronary Stents (1986) — Ulrich Sigwart and Jacques Puel implanted the first coronary stent in a human heart to prevent artery restenosis.
First TAVR Procedure (2002) — Alain Cribier performed the first Transcatheter Aortic Valve Replacement, revolutionizing treatment for aortic stenosis without open-heart surgery.

Current Cardiovascular Research & Breakthroughs

Gene-Editing for Lipid Lowering — Advanced base-editing and RNA therapies (such as VERVE-102) show potential for permanently reducing LDL cholesterol with single-dose targeted gene inactivation.
AI-Driven Predictive Diagnostics — Deep learning algorithms now evaluate polygenic risk scores and real-time imaging data to predict cardiac events years before clinical symptoms appear.
Stem Cell Remuscularization — Regenerative cardiac cell therapies using stem-cell-derived cardiomyocytes aim to repair post-infarct scar tissue and restore contractile function.
Pulsed-Field Ablation (PFA) — Non-thermal electroporation technology is transforming arrhythmia management by selectively isolating cardiac tissue with lower procedural risk.
Anti-Inflammatory Therapies — Target-specific anti-inflammatory drugs are being validated to reduce residual vascular risk and suppress ongoing atheroma plaque progression.
Transcatheter Valve Evolution (TMVR/TAVR) — Next-generation transcatheter systems are expanding treatment options for complex structural valve conditions without traditional open surgery.
Digital Twin Hemodynamic Modeling — Virtual patient-specific cardiac models integrate imaging and biomarkers to simulate interventional outcomes before execution.
Conduction System Pacing (LBBAP) — Left bundle branch area pacing is replacing traditional biventricular pacing to provide more natural physiological resynchronization.
Cardioprotective Metabolic Drugs — Broadening applications of SGLT2 inhibitors and GLP-1 receptor agonists demonstrate significant reductions in heart failure admissions and vascular events.
Novel Aldosterone Synthase Inhibitors — New drug classes like Baxdrostat provide target-specific control for resistant hypertension by directly modulating hormone pathways.